讲述二战时期的1945年，一群人在北大西洋上遇险漂流，遇到一艘希特勒部队的大船，原船员们都已血腥、离奇地死去，这群幸存者很快发现了原因：船上存放的古老棺材里，有嗜血的存在苏醒了。

恐怖分子企图劫持横越大西洋的夜间班机，身怀怪病的女子因而被迫亲上火线。为了保护儿子，她必须让黑暗的祕密曝光，释放出她一直设法压抑在体内的怪物。

Jailed under a tough cop, an uneducated politician decides to spend his time studying for high school, while his scheming wife has plans of her own.

The film tells the story of three people for a year: a son (Magimel) diagnosed with cancer, a mother (Deneuve) suffering from helplessness and a doctor (Cécile de France) to do her job: One year and four seasons for these three characters to deal with the disease, to tame it, and to understand what it means to die while alive.