在经历了一场疯狂的婚礼派对之后，喝的神志不清的艾博（塞巴斯蒂安·贝策尔 Sebastian Bezzel 饰）意外的被警察从酣睡中叫醒，一夜之间，他竟然从一名小镇警察沦为了凶杀案的嫌疑人，他被指控谋杀了名为巴什尔（弗兰西斯·富顿-史密斯 Francis Fulton-Smith 饰），因为在凶案现场，警方发现了艾博随身携带的小刀。　　就这样，艾博不得不再一次的为洗清自己身上的嫌疑而展开了对案件的调查，和他一起奋斗的还有他的好友卢迪（西蒙·舒瓦茨 Simon Schwarz 饰）。随着调查的深入，巴什尔的妻子（诺拉·冯·瓦尔茨特滕 Nora von Waldstätten 饰）渐渐浮出了水面，这个美丽又性感的女人隐藏着不为人知的过去。

Shipwreck survivors are found on Beiru Island (Infanto tô), which was previously used for atomic tests. The interior is amazingly free of radiation effects, and they believe that they were protected by a special juice that was given to them by the island's residents. A joint expedition of Rolisican and Japanese scientists explores Beiru and discovers many curious things, including two women only one foot (30 centimeters) high. Unscrupulous expedition leader Clark Nelson abducts the women and puts them in a vaudeville show. But their sweet singing contains a telepathic cry for help to Mothra, a gigantic moth that is worshiped as a deity by the island people. The giant monster heeds the call of the women and heads to Tokyo, wreaking destruction in its path.

2006年印尼日惹發生大地震，並將埋藏在地底、擁有兩公里長的頭骨化石暴露在人類的眼前，這項震驚世人的發現轟動了整個印尼，政府快速組成了研究小組以追蹤化石的起源，然而，政府官員以及科學家卻向公眾隱藏了關於該化石的秘密。直到某天印尼政府突然無預警關閉了研究小組進入化石區域的通道，一項駭人聽聞的恐懼陰霾即將朝人民襲來…